The only way I can see this “twist” paying off now for Regina is if SwanQueen happens or if she decides she’s better off without romance. However…I’m not sure what her “endgame” is now. Do Zelena and Regina become spinster sisters who own lots of cats?
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"That’s how you know you’ve really got a home. When you leave it, there’s this feeling that you can’t shake. You just miss it." Neal Cassidy