I don’t think they’ll kill off the regular minor characters eg Grumpy, Sneezy, Granny or Whale because they’re part of the small town charm that the show wants to get back to.
Actually I could see them killing off Granny. It would be the “best” way to bring Ruby back and have her take over the diner, which they set up as Granny’s wish back in S1 “Red Handed.”
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"He was a lot of things to me" "The only conclusion was love"