No, they won’t kill off Emma. Not only is she the show’s protagonist and audience insert, but the time to kill Emma already came and went. Emma dying to save her family in Swan Song and then her family getting her back from the UW would have made perfect narrative and mythical sense (since saviors have been known to die and be resurrected). However, they chose to go with making Hook into a dark one and then getting him back instead (which didn’t make sense). I predict Emma won’t die since Regina will save her from the Evil Queen. Regina defeating her own evil self will be Emma’s loophole to defeat her villain (aka the Evil Queen).
"That’s how you know you’ve really got a home. When you leave it, there’s this feeling that you can’t shake. You just miss it." Neal Cassidy