I think the villain angle is a good idea. The only problem being that that then creates the plot of let’s get back to our loved ones which is not an interesting plot. Though, if they have memory issues that could be why they aren’t trying to find the family, but that also is not an interesting plot. Both of those plots would just linger around until they ended and everyone would be fine. It could happen, but it isn’t good plot.
I agree it isn’t really a good plot, but I think that the core characters have memory loss. Henry tells Lucy that there isn’t a curse — meaning there probably is, but he doesn’t remember being cursed.
"That’s how you know you’ve really got a home. When you leave it, there’s this feeling that you can’t shake. You just miss it." Neal Cassidy