The wording “apple red as blood” probably has layered meanings. On the one hand, the obvious meaning is that “apple red” refers to the poisoned apple that Regina gives to Snow White. That could be the same apple that Regina had Hansel and Gretel retrieve from the blind witch. The second meaning is that “red as blood” could refer not only to the color of Snow White’s lips, but also to the blood which could be shed. The promo for the rest of season 1 makes it appear as if Regina threatens to have Prince Charming killed if Snow White doesn't comply and eat the apple. Regina appears to visit Prince Charming in prison, perhaps the same prison where King George is holding the prince captive (after episode 16).
"That’s how you know you’ve really got a home. When you leave it, there’s this feeling that you can’t shake. You just miss it." Neal Cassidy