I think Rumple’s experience with Belle likely inspired the curse. She’s not directly a part of it though, because he believes her to be dead. Which will make things interesting when Mr Gold finds out she’s alive, because he’s been very patient for several decades, waiting for events to play out to his advantage and Belle being in Storybrooke wasn’t a factor he’d considered in his plan, so that’ll come outta left field and totally throw him off.