Hook wants to settle down probably even more than Emma, he just wants to have something in life to keep him going. He doesn’t want adventure, he really now looks like he doesn’t want his revenge, all he wants is something to care and fight for.
Someone to love, that’s what Hook wants and he’s willing to give up everything including his revenge.
As for whether Hook can settle down, there’s a lot a woman can do to influence a man over time. I like that line from “My Big Fat Greek Wedding”. “The man is the head, but the woman is the neck” (and what can a head do without a neck?).
Love the “My Big Fat Greek Wedding” reference and totally applies.