The context is so hard to guess. It is true that purple is often magic (the smoke when magic came to town, Cora’s poofing color of choice). So I’m guessing a magic potion of some kind, and they definitely look concerned. I would guess they are working on the new curse.
I think going to NY to get some magical item would make sense. Neal definitely had a lot of random things in there! Yet it doesn’t look like HIS block, so maybe it is some new character they will meet? I remember once that someone summarized Ruby as “preventing Henry from intruding on the main plot” and perhaps that’s alas, the role Neal has right now. Someone has to do it!
“If I had a world of my own, everything would be nonsense. Nothing would be what it is, because everything would be what it isn't. And contrary wise, what is, it wouldn't be. And what it wouldn't be, it would. You see?” -- Lewis Carroll, Alice's Adventures in Wonderland & Through the Looking-Glass